It looks like Joseph Kissel married two women named Mary

1. Mary Anna Nuwer
2. Mary Anna Huber

I have Francis's birth / baptism record from St. Mary's which appears to list Joseph and Mary Nuwer as the parents with a birth date of 2/2/1855 and I see Mary's death date is listed as 2/2/1855, so perhaps she passed away in child birth?

Also interesting in the 1855 census I find a Joseph & Mary Kissel listed (taken 9-JUN-1855 so presumably after Mary Nuwer's death) which lists the following:

Joseph Kissel Mary - Wife Lewis Ambrose Child Joseph - Child Mary - Child Elizabeth - Child Francis - Child

It shows Joseph as being in the country for 5 years and Mary (presumably Huber) for 13. So I'm wondering if Lewis, Joseph, Mary, Elizabeth are children of Mary Huber's perhaps from a man named Ambrose who passed away widowing her and she later married Joseph? Interesting that Francis is also listed here as an Ambrose, but maybe it was just a lazy census taker...

In following census records, 1860, 65, 70, 75, All of the kids still living in the hose list their names as Kissel

So, my best guess here is this:

Mary Huber married a man named Ambrose and had 4 children (Lewis - 1843, Joseph 1845, Mary 1846, Elizabeth 1849) and her husband passes away sometime before 1855.

Joseph comes to the US around 1850, meets Mary Nuwer. They marry and she passes away in child birth with Francis in 1855

With both Mary Huber and Joseph Kissel now single they marry have have 2 more children (Henry 1856 and Magdalene 1858)

-- Tom Weichmann 18-MAY-2020